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What are the key features of the structure of the endothelium? Give an account of the main actions of NO. Describe how NO is produced, and how secretion is regulated. The Endothelium The endothelium is constructed of a layer of oblong shaped cells, constituting a simple squamous epithelium, lining the lumen of all blood vessels. The endothelial cells are 0.2-0.3 micrometers thick and are cobblestoned in a single layer, with narrow clefts (intercellular clefts) between them. The cytoplasm of the…